Nessus 4.2 is out.
I tried it out and I must say that the new UI is great. I am not a big fan of Flash and I regret this choice. However, the design is excellent, all options are accessible in a logical way. Instead of spreading over the options like it used to be, they come to you in the right order.
I also appreciate that the server and the client set-up are now unified thanks to the web interface (you can access it from localhost or from the network indifferently).
The report section has also been greatly improved.
So, if you were already an Nessus user, it is worth upgrading.
Talking about the set-up, there is an up-to-date package for openSUSE (of course, there are a lot less dependencies than before).